Stem Cells and Regenerative Medicine

hematopoietic stem cells
Ionizing radiation induced γH2AX foci in the DNA of human hematopoietic stem cells. Immunofluorescent microscopy image.

The field of Stems Cells and Regenerative Medicine is quickly growing, and Sackler researchers are incorporating the latest technologies and studies into their research in this area. 


"Musculoskeletal – Stem cells and Nanotechnology"

Prof. Dafna Benayahu, Ph.D., follows the differentiation of skeletal stem cells and their lineage fate. Research methods used include bioinformatics, gene cloning, qRT-PCR, cell biology analysis including immunofluorescence, scanning electron microscopy and biochemistry. Nanotechnology combines the cell fate differentiation with multidisciplinary approaches for the development of a new platform for cell analysis.


"DNA Damage Response in Normal and Leukemia Hematopoietic Stem Cells"

Dr. Michael Milyavsky, Ph.D.and his lab aim to understand how HSC cope with DNA damage to preserve normal blood regeneration and to limit the risk of leukemogenesis. They also seek to discover how leukemia stem cells escape therapy and try to devise strategies to prevent this from happening.


 "Cytoskeletal Regulation of Epidermal Stem Cells"

Dr. Chen Luxenburg, Ph.D. and his lab study how cytoskeleton-derived signals control stem cell’s ability to give rise to a functional tissue during development, to maintain it throughout life and repair it upon wounding.  


"Pancreas development and function in health and diabetes"

 Dr. Limor Landsman studies how proper pancreatic insulin production is achieved and maintained and why it is lost in diabetes. To this end, she and her team research beta-cell development and function, focusing on the role of the pancreatic microenvironment in these processes.


“Molecular biology of the kidney: from stem cells through development to human aging and cancer” 

 Dr. Oren Pleniceanu and his team in the Kidney Research Lab explore innovative ways of uncovering the mysteries of kidney development and stem cells and applying them to regenerate damaged organs, and also find new and exciting ways to combat aging through the study of cellular senescence. 


More research summaries available in the Research Brochure.


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