Stem Cells and Regenerative Medicine

hematopoietic stem cells
Ionizing radiation induced γH2AX foci in the DNA of human hematopoietic stem cells. Immunofluorescent microscopy image.

The field of Stems Cells and Regenerative Medicine is quickly growing, and Sackler researchers are incorporating the latest technologies and studies into their research in this area. 

 

"Musculoskeletal – Stem cells and Nanotechnology"

Prof. Dafna Benayahu, Ph.D., follows the differentiation of skeletal stem cells and their lineage fate. Research methods used include bioinformatics, gene cloning, qRT-PCR, cell biology analysis including immunofluorescence, scanning electron microscopy and biochemistry. Nanotechnology combines the cell fate differentiation with multidisciplinary approaches for the development of a new platform for cell analysis.

 

"DNA Damage Response in Normal and Leukemia Hematopoietic Stem Cells"

Dr. Michael Milyavsky, Ph.D.and his lab aim to understand how HSC cope with DNA damage to preserve normal blood regeneration and to limit the risk of leukemogenesis. They also seek to discover how leukemia stem cells escape therapy and try to devise strategies to prevent this from happening.

 

 "Cytoskeletal Regulation of Epidermal Stem Cells"

Dr. Chen Luxenburg, Ph.D. and his lab study how cytoskeleton-derived signals control stem cell’s ability to give rise to a functional tissue during development, to maintain it throughout life and repair it upon wounding.  

 

More research summaries available in the Research Brochure.

 

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