Stem Cells and Regenerative Medicine

hematopoietic stem cells
Ionizing radiation induced γH2AX foci in the DNA of human hematopoietic stem cells. Immunofluorescent microscopy image.

The field of Stems Cells and Regenerative Medicine is quickly growing, and Sackler researchers are incorporating the latest technologies and studies into their research in this area. 

 

"Musculoskeletal – Stem cells and Nanotechnology"

Prof. Dafna Benayahu, Ph.D., follows the differentiation of skeletal stem cells and their lineage fate. Research methods used include bioinformatics, gene cloning, qRT-PCR, cell biology analysis including immunofluorescence, scanning electron microscopy and biochemistry. Nanotechnology combines the cell fate differentiation with multidisciplinary approaches for the development of a new platform for cell analysis.

 

"Modeling the Nervous System in Development and Disease Using Pluripotent Stem Cells"

The lab of Dr. Yechiel Elkabetz, Ph.D., uses human embryonic stem cells to elucidate developmental programs in the
human nervous system, with particular focus on neural stem cells (NSCs). The main goal is to learn the biology of early neural stem cells in the lab in order to develop strategies for standardizing their growth in culture without loss of differentiation potential.

 

"DNA Damage Response in Normal and Leukemia Hematopoietic Stem Cells"

Dr. Michael Milyavsky, Ph.D.and his lab aim to understand how HSC cope with DNA damage to preserve normal blood regeneration and to limit the risk of leukemogenesis. They also seek to discover how leukemia stem cells escape therapy and try to devise strategies to prevent this from happening.

 

More research summaries available in the Research Brochure.

 

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