Prof. Gilad Twig

Epidemiology & Preventive Medicine
אפידמיולוגיה ורפואה מונעת סגל אקדמי קליני

General Information

Director of the Population Health Research Center, the Gertner Institute for Epidemiology and Health Policy Research, Sheba Medical Center Tel Hashomer.

 

Associate professor at the Department of Epidemiology and Preventive Medicine, School of Public Health, Faculty of Medical and Health Sciences, Tel Aviv University. 

CV

I completed my medical studies (1996-2004) with distinction at the Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. Concurrently, from 1999 to 2004, I completed my degree as a Doctor of Philosophy (PhD) from the Department of Physiology and Biophysics, Technion-Israel Institute of Technology, under the supervision of Prof. Ido Perlman.

From 2004-2005, I completed my medical internship and residency in internal medicine between 2011 and 2016, both at Sheba Medical Center, Tel Hashomer, in Israel. During this period (2011-2020), I was a member of the Talpiot Medical Leadership Program at Sheba Medical Center. 

Between 2006 and 2022, I served in various positions at the Medical Corps of Israel Defense Forces, including the head of the academy and research division and Chair of the medical residency committee. In 2019, I completed a Master's degree in Public Health (MPH) with distinction at the School of Public Health, Faculty of Medical and Health Sciences, Tel Aviv University.

 

In 2020, I was appointed as an Associate Professor at the Department of Epidemiology and Preventive Medicine, School of Public Health, Faculty of Medical and Health Sciences, Tel Aviv University.  Since 2022, I have been heading the population health research center, the Gertner Institute for Epidemiology and Health Policy  Research, Sheba Medical Center Tel Hashomer.

Research

Epidemiology of non-communicable diseases, focusing on cardiometabolic risk factors, morbidity, and mortality.

The impact of obesity in childhood and adolescence and other host-related and social exposures on long-term risk of cardiovascular diseases, hypertension, and cancer. 

Publications

Link to the full publication list in PubMed:

 https://pubmed.ncbi.nlm.nih.gov/?term=Twig+G+&sort=date

 

1: Tsur AM, Akavian I, Landau R, Derazne E, Tzur D, Vivante A, Grossman E, Rotem RS, Fishman B, Pinhas-Hamiel O, Afek A, Coresh J, Chodick G, Twig G. Adolescent Body Mass Index and Early Chronic Kidney Disease in Young Adulthood. JAMA Pediatr. 2024 ;178(2):142-150. doi: 10.1001/jamapediatrics.2023.5420. PMID: 38079159.

 

2: Nitecki M, Gerstein HC, Balmakov Y, Tsur E, Babushkin V, Michaeli T, Afek A, Pinhas-Hamiel O, Cukierman-Yaffe T, Twig G. High BMI and the risk for incident type 1 Diabetes Mellitus: a systematic review and meta-analysis of aggregated cohort studies. Cardiovasc Diabetol. 2023;22(1):300. doi: 10.1186/s12933-023-02007-y. PMID: 37919779.

 

3: Simchoni M, Derazne E, Pinhas-Hamiel O, Cukierman-Yaffe T, Bendor CD, Bardugo A, Chodick G, Tzur D, Endevelt R, Gerstein HC, Afek A, Twig G. Adolescent body mass index and cognitive performance: a nationwide study of 2.48 million Israeli adolescents. Eur J Endocrinol. 2023;188(7):630-640. doi: 10.1093/ejendo/lvad075. PMID: 37406222.

 

4: Fishman B, Bardugo A, Zloof Y, Bendor CD, Libruder C, Zucker I, Lutski M, Ram A, Hershkovitz Y, Orr O, Omer M, Furer A, Goldman A, Yaniv G, Tanne D, Derazne E, Tzur D, Afek A, Grossman E, Twig G. Adolescent Hypertension Is Associated With Stroke in Young Adulthood: A Nationwide Cohort of 1.9 Million Adolescents. Stroke. 2023 Jun;54(6):1531-1537. doi: 10.1161/STROKEAHA.122.042100.. PMID: 37139816.

 

5: Nitecki M, Shapiro G, Orr O, Levitin E, Sharshevsky H, Tzur D, Twig G, Shapira S. Association Between Body Mass Index and Nonspecific Recurrent Low Back Pain in Over 600,000 Healthy Young Adults. Am J Epidemiol. 2023;192(8):1371-1378. doi: 10.1093/aje/kwad102. PMID: 37083852.

 

6: Bardugo A, Bendor CD, Rotem RS, Tsur AM, Derazne E, Gerstein HC, Tzur D, Pinhas-Hamiel O, Cukierman-Yaffe T, Raz I, Hod M, Tirosh A, Lebenthal Y, Afek A, Chodick G, Twig G. Glucose intolerance in pregnancy and risk of early-onset type 2 diabetes: a population-based cohort study. Lancet Diabetes Endocrinol. 2023;11(5):333-344. doi: 10.1016/S2213-8587(23)00062-1 PMID: 37011646.

 

7: Peled A, Nitzan I, Megreli J, Derazne E, Tzur D, Pinhas-Hamiel O, Afek A, Twig G. Myopia and BMI: a nationwide study of 1.3 million adolescents. Obesity (Silver Spring). 2022;30(8):1691-1698. doi: 10.1002/oby.23482. PMID: 35894082.

 

8: Bendor CD, Bardugo A, Rotem RS, Derazne E, Gerstein HC, Tzur D, Pinhas-Hamiel O, Tsur AM, Cukierman-Yaffe T, Lebenthal Y, Afek A, Chodick G, Twig G. Glucose Intolerance in Pregnancy and Offspring Obesity in Late Adolescence. Diabetes Care. 2022;45(7):1540-1548. doi: 10.2337/dc21-2634. PMID: 35670776.

 

9: Zucker I, Zloof Y, Bardugo A, Tsur AM, Lutski M, Cohen Y, Cukierman-Yaffe T, Minsky N, Derazne E, Tzur D, Melzer Cohen C, Pinhas-Hamiel O, Chodick G, Raz I, Afek A, Gerstein HC, Tirosh A, Twig G. Obesity in late adolescence and incident type 1 diabetes in young adulthood. Diabetologia. 2022;65(9):1473-1482. doi: 10.1007/s00125-022-05722-5. PMID: 35665825.

 

10: Tsur AM, Akavian I, Derazne E, Tzur D, Vivante A, Grossman E, Rotem RS, Fishman B, Afek A, Coresh J, Chodick G, Twig G. Adolescent Blood Pressure and the Risk for Early Kidney Damage in Young Adulthood. Hypertension. 2022 ;79(5):974-983. doi: 10.1161/HYPERTENSIONAHA.121.18748. PMID: 35253445.

 

11: Chodick G, Omer-Gilon M, Derazne E, Puris G, Rotem R, Tzur D, Pinhas-Hamiel O, Cukierman-Yaffe T, Shina A, Zucker I, Tirosh A, Afek A, Shalev V, Twig G. Adolescent body mass index and changes in pre-pregnancy body mass index in relation to risk of gestational diabetes. EClinicalMedicine. 2021;42:101211. doi: 10.1016/j.eclinm.2021.101211. PMID: 34849479.

 

12: Lutski M, Zucker I, Bardugo A, Bendor CD, Derazne E, Tzur D, Novick D, Raz I, Pinhas-Hamiel O, Mosenzon O, Afek A, Gerstein HC, Twig G, Cukierman-Yaffe T. Adolescent cognitive function and incident early-onset type 2 diabetes. EClinicalMedicine. 2021;41:101138. doi: 10.1016/j.eclinm.2021.101138. PMID: 34622185.

 

13: Peled A, Raz I, Zucker I, Derazne E, Megreli J, Pinhas-Hamiel O, Einan- Lifshitz A, Morad Y, Pras E, Lutski M, Cukierman-Yaffe T, Mosenzon O, Tzur D, Tirosh A, Gerstein HC, Afek A, Twig G. Myopia and Early-Onset Type 2 Diabetes: A Nationwide Cohort Study. J Clin Endocrinol Metab. 2022;107(2):e663-e671. doi: 10.1210/clinem/dgab669. PMID: 34505129.

 

14: Fishman B, Grossman E, Zucker I, Orr O, Lutski M, Bardugo A, Bendor CD, Leiba Y, Cukierman-Yaffe T, Derazne E, Mosenzon O, Tzur D, Beer Z, Pinhas-Hamiel O, Fishman T, Afek A, Tirosh A, Raz I, Gerstein HC, Twig G. Adolescent Hypertension and Risk for Early-Onset Type 2 Diabetes: A Nationwide Study of 1.9 Million Israeli Adolescents. Diabetes Care. 2021;44(1):e6-e8. doi: 10.2337/dc20-1752. PMID: 33148634.

 

15: Furer A, Afek A, Sommer A, Keinan-Boker L, Derazne E, Levi Z, Tzur D, Tiosano S, Shina A, Glick Y, Kark JD, Tirosh A, Twig G. Adolescent obesity and midlife cancer risk: a population-based cohort study of 2·3 million adolescents in Israel. Lancet Diabetes Endocrinol. 2020 Mar;8(3):216-225. PMID: 32027851.

16: Twig G, Yaniv G, Levine H, Leiba A, Goldberger N, Derazne E, Ben-Ami Shor D, Tzur D, Afek A, Shamiss A, Haklai Z, Kark JD. Body-Mass Index in 2.3 Million Adolescents and Cardiovascular Death in Adulthood. N Engl J Med. 2016;374(25):2430-40. doi: 10.1056/NEJMoa1503840. Epub 2016 Apr 13. PMID: 27074389.

 

17: Calderon-Margalit R, Golan E, Twig G, Leiba A, Tzur D, Afek A, Skorecki K, Vivante A. History of Childhood Kidney Disease and Risk of Adult End-Stage Renal Disease. N Engl J Med. 2018 ;378(5):428-438. doi: 10.1056/NEJMoa1700993. PMID: 29385364.

Prizes

2022-2024 IDF Medical Corps "Risk factors at adolescence for cardiovascular disease at young adulthood".

2022-2025 Israeli Ministry of Health "Lifestyle interventions to reduce burden of gestational diabetes among Arab Israeli women"

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