The Wnt Signaling Pathway and Colorectal Cancer
Dr. Rina Rosin-Arbesfeld, Ph.D.
Department of Clinical Microbiology and Immunology
The Wnt signaling pathway is involved in virtually every aspect of human development, as well as in adult homeostasis. Hyperactivation of this pathway has been linked to a wide range of cancers and especially colorectal cancer. Our aim is to understand the molecular events underlying Wnt signal transduction, as well as develop novel therapeutic strategies to fight colorectal cancer.
Current projects in the lab include:
- Identifying and characterizing new Wnt signaling components.
- Developing new anti-colorectal cancer treatment strategies.