Proteomics of Breast Cancer Progression

Our main interest is to understand the mechanisms of breast cancer progression. We are using state-of-theart mass spectrometry-based proteomics to obtain a system-wide view of the tumor proteins. Analysis of the changes in protein levels and modifications that occur during tumor development is aimed to discover novel regulators of transformation.

Combination of the proteomics technology with biochemical and genetic methods will show the significance of these candidates to cancer development and may suggest novel drug targets and tumor markers.