Emeritus Professor, Department of Physiology & Pharmacology, Tel Aviv University
Prof. Dov Lichtenberg
Emeritus in Physiology Pharmacology
פיזיולוגיה ופרמקולוגיה
אמריטוס
Email: physidov@tauex.tau.ac.il
Phone: 03-6407305
Fax: 03-6405246
Office: Sackler School of Medicine, 505
Positions
Biography
Prof. Dov Lichtenberg was born in Jerusalem in 1942 and graduated from high school in Tel Aviv in 1960. He is married with four children and 12 grandchildren.
Education:
| 1963 | B.Sc. in Chemistry | Hebrew University |
| 1967 | M.Sc. in Chemistry | Hebrew University |
| 1972 | Ph.D. in Chemistry | Hebrew University |
| 1972-1974 | Post-Doctoral Studies in Chemical Biophysics | California Institute of Technology |
Research
Much of our ongoing research during the past 30 years addresses two issues:
- Oxidative modification of lipids in membranes and in plasma lipoproteins, dependence of the oxidation resistance of lipids on various factors, including physiological and pathological conditions, including lipid dislipodemiaand antioxidants and basic aspects of the mechanics involved in lipid oxidation, using both lipoproteins and liposomalmodel systems.
- Solubilization of lipids, phospholipids and membranes by detergents. These processes are of significance with respect to solubilizationand reconstitution of biological membranceas well as in the naturally-occurring solubilization of dietary lipids (including cholesterol). Our studies address mechanistic, thermodynamic and structural aspects of these processes.
Recent Publications
Partial list of recent critical reviews
Dov Lichtenberg, Hasna Ahyayauch, Alicia Alonso, and Felix M. Goni, 2013. Detergent solubilization of lipid bilayers: a balance of driving forces. Trends in Biochemical Sciences, 2013, 38, 85-93.
Dov Lichtenberg, Hasna Ahyayauch, and Felix M. Goni, 2013.The Mechanism of Detergent Solubilization of Lipid Bilayers. Biophysical Journal 105 289–299.
Pinchuk, I., Lichtenberg, D., 2013. Analysis of the kinetics of lipid peroxidation in terms of characteristic time-points. Chem. Phys. Lipids, In Press.
Dov Lichtenberg, Ilya Pinchuk, 2013. Atherogenesis, the oxidative LDL modification hypothesis revisited, Advances Bioscience & Biotechnology, 4, 48-61.
Finkler M, Lichtenberg D, Pinchuk I, 2013 The relationship between oxidative stress and exercise. J Basic Clin Physiol. Pharmacol 17:1-11
Pinchuk, I., Shoval, H., Dotan, Y., and Lichtenberg, D., 2012. Evaluation of antioxidants: Scope, limitations and relevance of assays. Chemistry and Physics of lipids,
