Prof. Nir Osherov

Clinical Microbiology and Immunology

מיקרוביולוגיה ואימונולוגיה קלינית סגל אקדמי בכיר

Email: nosherov@tauex.tau.ac.il

Phone: 03-6409599

Another phone: 03-6409946

Fax: 03-6409160

My CRIS profile

Lab Website

Office: School of Medicine

Positions

Professor Nir Osherov

Fungal and antifungal research Lab (Room 843)

Director Ella Kodesz Institute of Host Defense against Infectious Diseases

Head of BSc Program in Medical and Life Sciences

Department of Clinical Microbiology and Immunology

Faculty of Medical and Health Sciences

Tel-Aviv University

Biography

Education

1984-1988	B.Sc, Biology	Hebrew University
1988-1994	Ph.D., Biochemistry	Hebrew University
1994-1996	Post-Doctoral studies. Dictyostelium development	University of California- San Diego
1996-2001	Post-doctoral studies. Aspergillus biology	Baylor College of Medicine and MD Anderson Cancer Center

Research

Human Mold Infections

Aspergillus fumigatus is the most common mold pathogen of human beings, causing invasive diseases in immunocompromised (cancer after chemotherapy, bone marrow transplant etc) patients. Poor diagnostic tools and the ineffectiveness of antifungal drugs against established Aspergillus infections combine to result in high mortality following A. fumigatus infection. Left untreated, mortality rates from invasive pulmonary aspergillosis (IPA) exceed 90% and even following aggressive antifungal treatment fatality rates of 50-70% are common.

The goals of my lab are:

To understand what enables this mold to be such an effective and dangerous pathogen of immunocompromised patients
To develop novel modes of treatment including new antifungal compounds, targeted antibodies and nano medicines.

Publications & Grants

see

https://cris.tau.ac.il/en/persons/nir-osherov/publications/