Dr. Moshe Parnas

פיזיולוגיה ופרמקולוגיה סגל אקדמי בכיר
Dr. Moshe Parnas
Phone: 03-6406541
Office: Sackler School of Medicine, 6

Positions

Senior Lecturer, Department of Physiology and Pharmacology, Sackler Faculty of Medicine and Sagol School of Neuroscience

 

Research

Neural Circuits and Olfactory Perception in Drosophila

We are exploring the various mechanisms by which neural circuits encode information and support behaviour, learning and memory. In addition, we are studying how the connectivity and activity of such circuits and neural networks are affected by molecular mechanisms underlying brain disorders. We use a multidisciplinary approach, with the Drosophila olfaction system as our model system. Our studies incorporate in vivo whole cell patch recordings, in vivo functional imaging, behaviour experiments, molecular biology, mathematical modelling and genetics.

 

Projects in the lab include:

  1. Intensity and identity coding in a multidimensional sensory system – the Drosophila olfactory system.
  2. Neuropeptidergic modulation of olfaction and its effect on odour perception.
  3. The role of deregulated channel proteins and altered neuronal function in Frontotemporal Dementia.
  4. A novel multifaceted approach to study the mechanisms underlying the effects of human genes associated with schizophrenia using Drosophila.

 

Publications

Manuscripts

Parnas, M., Lin, A.C., Huetteroth. W., and Miesenböck, G. (2013). Odor discrimination in Drosophila: From neural population code to behavior. Neuron, 79:932-944.

 

Peters, M., Trembovler, V., Alexandrovich, A., Parnas, M., Birnbaumer, L., Minke, B., and Shohami, E. (2012). Carvacrol together with TRPC1 elimination improve functional recovery after traumatic brain injury in mice. Journal of Neurotrauma 29:2831-4.

 

 

Review

Parnas, M., Peters, M., and Minke, B. (2012). Biophysics of TRP Channels. Editor: Edward H. Egelman, In: Comprehensive Biophysics, Vol 6, Channels Proteins, Mauricio Montal. Oxford: Academic Press, pp. 68-107.

 

 

Grants

  • 2016 NIPI – National Institute of Psychobiology in Israel
  • 2017-2019 United States-Israel Binational Science Foundation
  • 2016-2020 ERC Starting Grant

 

Tel Aviv University, P.O. Box 39040, Tel Aviv 6997801, Israel
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