Prof. Daniel[Dani] Cohen

Emeritus in School of Public Health
Medicine Dean & Assoc. Deans
ביה"ס לבריאות הציבור אמריטוס
Prof. Daniel[Dani] Cohen
Phone: 03-6407081
Fax: 03-6409868


Professor, Epidemiology and Preventive Medicine, School of Public Health, Tel Aviv University

Chair, Middle East Consortium Middle East Consortium on Infectious Disease Surveillance (MECIDS)

Diana & Stanley Steyer Chair of Cancer Prevention and Control

Co-Founder and Director, Summer Institute of Advanced Epidemiology and Preventive Medicine, Tel Aviv University

Head, Tiberio Swartz Research Forum on Epidemiology of Infectious Diseases and Biosecurity


Professor Daniel (Dani) Cohen joined Tel Aviv University (TAU) for a full-time academic position in 2002 and has been a full Professor since 2007. Previously, he served in the Israel Defense Forces for many years and was the Director of the Infectious Diseases Research Institute in the Medical Corps. Prof. Cohen served as the Head of Tel Aviv University School of Public Health for 6 years, after serving 4 years as Chair of the Department of Epidemiology and Preventive Medicine. Prof. Cohen is currently the Diana & Stanley Steyer Chair of Cancer Prevention and Control.   

Prof. Cohen founded the Tiberio Swartz Forum on Epidemiology of Infectious Diseases and Biosecurity, a very active national and international stage for scientific communications and discussions in the field of infectious diseases and vaccines. Additionally, he is the co-founder and co-director of the Summer International Institute of Advanced Epidemiology and Preventive Medicine at TAU School of Public Health. He also serves as an executive board member and the current Chairperson of the Middle East Consortium for Infectious Diseases Surveillance (MECIDS) and acts on various national and international advisory boards in the field of infectious diseases and vaccines. Prof. Cohen has been a consultant for the World Health Organization (WHO) on several occasions. In November 2020 Prof. Cohen was appointed to the WHO Technical Advisory Group on candidate vaccine prioritization (TAG-CVP).

Prof. Cohen has supervised many graduate and post-graduate students. He has received several awards for his outstanding contribution to research and has authored over 280 peer-reviewed articles.


Click here to view Prof. Cohen's CV (Short Version).​


Research Interests

  • Epidemiology of infectious diseases
  • Vaccinology
  • Development and evaluation of enteric vaccines
  • Risk and protective host factors associated with enteric diseases and in particular: shigellosis
  • Study of the association between selected infectious agents (e.g. Helicobacter pylori, Human Papilloma Virus) and cancer 


Selected Publications

Click here for a complete list of Prof. Cohen's Peer-Reviewed Articles. 

Publications (from the last three years)

Armon R, Frenkel M, Cohen D, Segal E. Dermatomycoses in the Israeli defense forces-Epidemiological and clinical aspects. Mycoses. 2020;63(1):65-70.

Mazaba ML, Siziya S, Monze M, Cohen D. Epidemiology of acute rubella infection in Zambia during the pre-vaccination period (2005-2016) as a baseline for monitoring rubella epidemiology in the post-rubella vaccine introduction era. BMC infectious diseases. 2020;20(1):7.

Muhsen K, Na'amnih W, Adler A, Carmeli Y, Cohen D. Clostridium difficile-associated disease and Helicobacter pylori seroprevalence: A case-control study. Helicobacter. 2020;25(1):6.

Bassal R, Indenbaum V, Pando R, Levin T, Shinar E, Amichay D, Barak M, Ben-Dor A, Haim AB, Mendelson E, Cohen D, Shohat T. Seropositivity of measles antibodies in the Israeli population prior to the nationwide 2018 - 2019 outbreak. Hum Vaccin Immunother. 2020;29:1-5. 

Maor Y, Cohen D, Paran N, Israely T, Ezra V, Axelrod O, Shinar E, Izak M, Rahav G, Rahimi-Levene N, Bazofin BM, Gelman R, Dicker D, Brosh-Nissimov T, Megged O, Dahan D, Benov A, Paz A, Edward K, Moran A, Rogowski O, Sorkine P, Mayo A, Zimhony O, Chen J. Compassionate use of convalescent plasma for treatment of moderate and severe pneumonia in COVID-19 patients and association with IgG antibody levels in donated plasma. EClinicalMedicine. 2020;26

Na'amnih W, Carmeli Y, Asato V, Goren S, Adler A, Cohen D, Muhsen K. Enhanced Humoral Immune Responses against Toxin A and B of Clostridium difficile is Associated with a Milder Disease Manifestation. J Clin Med. 2020;9(10):3241.

Munitz A, Edry-Botzer L, Itan M, Tur-Kaspa R, Dicker D, Marcoviciu D, Goren MG, Mor M, Lev S, Gottesman T, Muhsen K, Cohen D, Stein M, Qimron U, Freund NT, Wine Y, Gerlic M. Rapid seroconversion and persistent functional IgG antibodies in severe COVID-19 patients correlates with an IL-12p70 and IL-33 signature. Scientific reports. 2021;11(1):1-3.

Bassal R, Cohen D, Green MS, Keinan-Boker L. The Israel National Sera Bank: Methods, Representativeness, and Challenges. Int J Environ Res Public Health. 2021;18(5):2280.

Bassal R, Keinan-Boker L, Cohen D. A Significant Decrease in the Incidence of Shigellosis in Israel during COVID-19 Pandemic. Int J Environ Res Public Health. 2021;18(6):3070.

Izak M, Yahalom V, Maor Y, Zimhoni O, Cohen D, Chen J, Shinar E. COVID-19 - Blood groups, antibodies and convalescent plasma. [HEBREW]. Harefuah. 2021;160(3):139-143.

Cohen D, Atsmon J, Artaud C, Meron-Sudai S, Gougeon M-L, Bialik A, Goren S, Asato V, Ariel-Cohen O, Reizis A, Dorman A, Hoitink CWG, Westdijk J, Ashkenazi S, Sansonetti P, Mulard LA, Phalipon A.  Safety and immunogenicity of a synthetic carbohydrate conjugate vaccine against Shigella flexneri 2a in healthy adult volunteers: a phase 1, dose escalating, single-blind, randomised, placebo-controlled study. Lancet Infect Dis. 2021;21(4):546-558.

Chisenga CC, Bosomprah S, Simuyandi M, Mwila-Kazimbaya K, Chilyabanyama ON, Laban NM, Bialik A, Asato V, Meron-Sudai S, Frankel G, Cohen D, Chilengi R. Shigella-specific antibodies in the first year of life among Zambian infants: A longitudinal cohort study. PLoS One. 2021;16(5):e0252222.

Bassal R, Indenbaum V, Pando R, Levin T, Shinar E, Amichay D, Barak M, Ben-Dor A, Haim AB, Mendelson E, Cohen D, Shohat T. Seropositivity of measles antibodies in the Israeli population prior to the nationwide 2018 - 2019 outbreak. Hum Vaccin Immunother. 2021;4;17(5):1353-1357.

Chodick G, Tene L, Patalon T, Gazit S, Ben Tov A, Cohen D, Muhsen K. Assessment of Effectiveness of 1 Dose of BNT162b2 Vaccine for SARS-CoV-2 Infection 13 to 24 Days After Immunization. JAMA Netw Open. 2021;4(6):e2115985.

Muhsen K, Schwaber MJ, Bishara J, Kassem E, Atamna A, Na'amnih W, Goren S, Bialik A, Mohsen J, Zaide Y, Hazan N, Ariel-Cohen O, Cohen R, Shitrit P, Marchaim D, Benenson S, Ben-David D, Rubinovitch B, Gotessman T, Nutman A, Wiener-Well Y, Maor Y, Carmeli Y, Cohen D. Sero-Prevalence and Sero-Incidence of Antibodies to SARS-CoV-2 in Health Care Workers in Israel, Prior to Mass COVID-19 Vaccination. Front Med (Lausanne). 2021;8:689994.

Muhsen K, Na'aminh W, Lapidot Y, Goren S, Amir Y, Perlman S, Green MS, Chodick G, Cohen D. A nationwide analysis of population group differences in the COVID-19 epidemic in Israel, February 2020-February 2021. Lancet Reg Health Eur. 2021;7:100130.

Iflah M, Kassem E, Rubinstein U, Goren S, Ephros M, Cohen D, Muhsen K. Convulsions in children hospitalized for acute gastroenteritis. Scientific Reports. 2021;11(1):1-8.

Muhsen K, Maimon N, Mizrahi A, Bodenneimer O, Cohen D, Maimon M, Grotto I, Dagan R. Effectiveness of BNT162b2 mRNA COVID-19 vaccine against acquisitions of SARS-CoV-2 among health care workers in long-term care facilities: a prospective cohort study. 2021. SSRN 3885633

Muhsen K, Cohen D. COVID-19 vaccination in Israel. Clinical Microbiology and Infection. 2021;27(11):1570-4.

Lapidot Y, Reshef L, Cohen D, Muhsen K. Helicobacter pylori and the intestinal microbiome among healthy school‐age children. Helicobacter. 2021;26(6):e12854.

MacLennan CA, Talaat KR, Kaminski RW, Cohen D, Riddle MS, Giersing BK. Critical needs in advancing Shigella vaccines for global health. The Journal of Infectious Diseases. 2022;225(9):1500-3.

Chodick G, Tene L, Rotem RS, Patalon T, Gazit S, Ben-Tov A, Weil C, Goldshtein I, Twig G, Cohen D, Muhsen K. The effectiveness of the Two-Dose BNT162b2 vaccine: analysis of real-world data. Clin Infect Dis. 2022;74(3):472-8

Izak M, Gendelman V, Bransburg-Zabary S, Stoyanov E, Gat R, Cohen D, Chen J, Maor Y, Benov A, Lev B, Zimhony O, Shinar E. Qualifying coronavirus disease 2019 convalescent plasma donors in Israel. Vox Sang. 2022;117(2):185-92.

Yahalom-Ronen Y, Erez N, Fisher M, Tamir H, Politi B, Achdout H, Melamed S, Glinert I, Weiss S, Cohen-Gihon I, Israeli O…,Cohen D,…Paran N. Neutralization of SARS-CoV-2 variants by rVSV-ΔG-spike-elicited human sera. Vaccines. 2022;10(2):291.

Mathur S, Banai M, Cohen D. Natural Brucella melitensis Infection and Rev. 1 Vaccination Induce Specific Brucella O-Polysaccharide Antibodies Involved in Complement Mediated Brucella Cell Killing. Vaccines. 2022;10(2):317.

Edelman-Klapper H, Zittan E, Shitrit AB, Rabinowitz KM, Goren I, Avni-Biron I, Ollech JE, Lichtenstein L, Banai-Eran H, Yanai H, Snir Y…Cohen D, Dotan I, REsponses to COVid-19 vaccinE IsRaeli IBD group (RECOVER). Lower serologic response to COVID-19 mRNA vaccine in patients with inflammatory bowel diseases treated with anti-TNFα. Gastroenterology. 2022;162(2):454-67.

Gazit S, Shlezinger R, Perez G, Lotan R, Peretz A, Ben-Tov A, Herzel E, Alapi H, Cohen D, Muhsen K, Chodick G, Patalon T. The Incidence of SARS-CoV-2 Reinfection in Persons With Naturally Acquired Immunity With and Without Subsequent Receipt of a Single Dose of BNT162b2 Vaccine: A Retrospective Cohort Study. Annals of Internal Medicine. 2022;175(5):674-81.

Lapidot Y, Reshef L, Maya M, Cohen D, Gophna U, Muhsen K. Socioeconomic disparities and household crowding in association with the fecal microbiome of school-age children. NPJ biofilms and microbiomes. 2022;8(1):1-2.

Gazit S, Shlezinger R, Perez G, Lotan R, Peretz A, Ben-Tov A, Herzel E, Alapi H, Cohen D, Muhsen K, Chodick G, Patalon T. SARS-CoV-2 Naturally Acquired Immunity vs. Vaccine-induced Immunity, Reinfections versus Breakthrough Infections: a Retrospective Cohort Study. Clinical Infectious Diseases. 2022;75(1):e545-e551.

Bassal R, Shohat T, Levin T, Pando R, Shinar E, Amichay D, Barak M, Ben-Dor A, Bar-Haim A, Mendelson E, Cohen D, Keinan-Boker L, Indenbaum V. The Concordance between Mumps and Rubella Sero-Positivity among the Israeli Population in 2015. Vaccines. 2022;10(7):996.

Rabinowitz KM, Navon M, Edelman-Klapper H, Zittan E, Bar-Gil Shitrit A, Goren I, Avni-Biron I, Ollech JE, Lichtenstein L, Banai-Eran H, Yanai H...Cohen D,..on behalf of the Responses to COVID-19 Vaccine Israeli IBD Group. Anti-TNFα Treatment Impairs Long-Term Immune Responses to COVID-19 mRNA Vaccine in Patients with Inflammatory Bowel Diseases. Vaccines. 2022;10(8):1186.

Meron-Sudai S, Reizis A, Goren S, Bialik A, Hochberg A, Cohen D. Pentraxin 3 and Shigella LPS and IpaB Antibodies Interplay to Defeat Shigellosis. Journal of Clinical Medicine. 2022;11(15):4384.

Muhsen K, Maimon N, Mizrahi AY, Varticovschi B, Bodenheimer O, Cohen D, Dagan R. Association of BNT162b2 Vaccine Third Dose Receipt With Incidence of SARS-CoV-2 Infection, COVID-19–Related Hospitalization, and Death Among Residents of Long-term Care Facilities, August to October 2021. JAMA Network Open. 2022;5(7):e2219940.

Muhsen K, Maimon N, Mizrahi AY, Boltyansky B, Bodenheimer O, Diamant ZH, Gaon L, Cohen D, Dagan R. Association of receipt of the fourth BNT162b2 dose with omicron infection and COVID-19 hospitalizations among residents of long-term care facilities. JAMA Internal Medicine. 2022;182(8):859-67.

Cohen D, Ashkenazi S, Schneerson R, Farzam N, Bialik A, Meron-Sudai S, Asato V, Goren S, Baran TZ, Muhsen K, Gilbert PB, MacLennan CA. Threshold protective levels of serum IgG to Shigella lipopolysaccharide: re-analysis of Shigella vaccine trials data. Clinical Microbiology and Infection. 2022;29(3):366-71.

Bassal R, Keinan-Boker L, Cohen D, Mendelson E, Lustig Y, Indenbaum V. Estimated Infection and Vaccine Induced SARS-CoV-2 Seroprevalence in Israel among Adults, January 2020–July 2021. Vaccines. 2022;10(10):1663.

Avni Biron I, Maayan Y, Mishael T, Hadar E, Neeman M, Plitman Mayo R, Sela HY, Yagel S, Goldenberg R, Ben Ya’acov A, Grisaru Granovsky S, Ollech JE, Edelman-Klapper H, Rabinowitz KM, Pauker MH, Yanai H, Goren S, Cohen D, Dotan I, Bar-Gil Shitrit A. SARS-CoV-2 IgG Antibody Levels in Women with IBD Vaccinated during Pregnancy. Vaccines. 2022;10(11):1833

Mathur S, Bardenstein S,Cohen D, Banai M. Serum PCR Diagnosis of Brucella melitensis Infection in Rev. 1 Vaccinated Sheep. Microbiology Research. 2022;14(1):21-33.

Donkor ES, Muhsen K, Johnson SAM, Kotey FCN, Dayie NTKD, Tetteh-Quarcoo PB, Tette EMA, Osei M-M, Egyir B, Nii-Trebi NI, Owusu-Okyere G, Owusu-Ofori A, Amir Y, Perlman S, Lopes PH, Mfodwo A, Gordon NC, Gresham L, Smolinski M, Cohen D. Multicenter Surveillance of Antimicrobial Resistance among Gram-Negative Bacteria Isolated from Bloodstream Infections in Ghana. Antibiotics. 2023;12(2):255.

Cohen D, Izak M, Stoyanov E, Mandelboim M, Perlman S, Amir Y, Goren S, Bialik A, Kliker L, Atari N, Yishai R, Zaide Y, Marcus H, Madar-Balakirski N, Israely T, Paran N, Zimhony O, Shinar E, Maor Y, Muhsen K. Predictors of reinfection with pre-Omicron and Omicron variants of concern among individuals who recovered from COVID-19 in the first year of the pandemic. International Journal of Infectious Diseases. 2023;132:72-9.

Miti S, Chilyabanyama ON, Chisenga CC, Chibuye M, Bosomprah S, Mumba C, Chitondo S, Siziya S, Cohen D, Chilengi R, Simuyandi M. Sensitivity and predictive value of dysentery in diagnosing shigellosis among under five children in Zambia. Plos one. 2023;18(2):e0279012.

Meron-Sudai S, Asato V, Adler A, Bialik A, Goren S, Ariel-Cohen O, Reizis A, Mulard LA, Phalipon A, Cohen D. A Shigella flexneri 2a synthetic glycan-based vaccine induces a long-lasting immune response in adults. npj Vaccines. 2023;8(1):35.

Bassal R, Davidovich-Cohen M, Yakunin E, Rokney A, Ken-Dror S, Strauss M, Wolf T, Sagi O, Amit S, Moran-Gilad J, Treygerman O, Karyo R, Keinan-Boker L, Cohen D. Trends in the Epidemiology of Non-Typhoidal Salmonellosis in Israel between 2010 and 2021. International Journal of Environmental Research and Public Health. 2023:24;20(9):5626.

Lapidot Y, Maya M, Reshef L, Cohen D, Ornoy A, Gophna U, Muhsen K. Relationships of the gut microbiome with cognitive development among healthy school-age children. Frontiers in Pediatrics. 2023;11:1198792.

Mazaba ML, Bosomprah S, Cohen D, Monze M, Siziya S. Estimated incidence and transmission intensity of rubella infection in Zambia pre-vaccine era 2005–2016. Epidemiology & Infection. 2023;151:e9.

Maor Y, Shinar E, Izak M, Rahav G, Brosh-Nissimov T, Kessler A, Rahimi-Levene N, Benin-Goren O, Cohen D, Zohar I, Alagem N, Castro S, Zimhony O. A Randomized Controlled Study Assessing Convalescent Immunoglobulins vs Convalescent Plasma for Hospitalized Patients With Coronavirus 2019. Clinical Infectious Diseases. 2023:ciad305.

Edelman-Klapper H, Rabinowitz KM, Zittan E, Shitrit AB, Goren I, Avni-Biron I, Ollech JE, Lichtenstein L, Banai-Eran H, Yanai H, Snir Y, Pauker MH, Friedenberg A, Levy-Barda A, Broitman Y, Ben Zvi H, Perets TT, Eliakim R, Barkan R, Goren S, Cohen D, Dotan I. Serologic Response and Safety after a Third Dose of the COVID-19 BNT162b2 Vaccine in Patients with Inflammatory Bowel Diseases. Vaccines. 2023;20;11(7):1263.



Cohen D, Meron-Sudai S, Bialik A, Asato V, Ashkenazi S. Detoxified O-Specific Polysaccharide (O-SP)–Protein Conjugates: Emerging Approach in the Shigella Vaccine Development Scene. Vaccines. 2022;10(5):675.


Clinical Study Protocols

"A Phase I Dose Escalation Study to Assess the Safety and Immunogenicity of the SF2a-TT15 Conjugate Vaccine against S. flexneri 2a in Healthy Adult Volunteers." 2015. Click here to view. 

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