Amalia Biron Research Institute of Thrombosis and Hemostasis

Director

Prof. Tami Livnat Ph.D

Associate Professor - Faculty of Hematology, Tel Aviv University

I completed my Ph.D. studies at Bar-Ilan University and conducted postdoctoral training at Tel Aviv University. Throughout my career, I have been driven by a deep-rooted passion for advancing research in thrombosis and hemostasis, with the ultimate goal of enhancing patient care. My research focuses on two interrelated aspects of coagulation factor activities. First, concerning the plasma-related activities of coagulation factors, we aim to develop comprehensive laboratory assays for assessing the coagulation status of patients. This includes diagnosing rare bleeding disorders, evaluating novel therapeutic interventions, and exploring anticoagulant systems. Simultaneously, we explore the cellular signaling activities induced by coagulation factors. My particular fascination lies in the multi-target, multi-action cytoprotective activities of the natural anticoagulant, activated protein C (APC). To advance this exploration, I established a collaborative research group with the Institute of Thrombosis & Hemostasis at Sheba Medical Center, the Ophthalmology Division at Rabin Medical Center, and the Laboratory of Eye Research at the Felsenstein Research Center. Our collective efforts are dedicated to developing innovative therapeutic approaches based on APC and its analogs for neurodegenerative ocular pathologies, ultimately preserving patients' vision.

The soul of my work is built on teamwork, bringing together dedicated researchers and physicians, and is funded by competitive basic science and industry-driven grants. This perfectly aligns with the Amalia Biron Research Institute of Thrombosis and Hemostasis's character of joining together basic and clinical research. I'm proud to have been an integral part of this institution since its establishment.

Publications (PubMed):  Livnat T - Search Results - PubMed