The Molecular Basis of the Regulation of Immune and Cancer Cells by Ion Channels

Projects in the lab include:

1. Identification of the molecular determinants governing the activation of Ca2+-activated chloride channels.
2. Elucidate the molecular rearrangements and architecture of membrane-embedded anion conductive Chloride Intracellular Channel (CLIC).
3. Explore the functional expression and physiological importance of anion channels in resting and activated microglia