Isotopes

Radioisotopes are defined as atoms that contain an unstable combination of neutrons and protons, or excess energy in their nucleus. Atoms with an unstable nucleus regain stability by shedding excess particles and energy in the form of radiation (radioactive decay)

Radioisotopes are defined as atoms that contain an unstable combination of neutrons and protons, or excess energy in their nucleus. Atoms with an unstable nucleus regain stability by shedding excess particles and energy in the form of radiation (radioactive decay)

 

List of isotopes used at Sackler Faculty of Medicine (see links for each isotope)

 

Isotope

Radioactive

decay

Source

Half-life

Years (y), days (d) hours (h)

Application

Cs - 137

Beta

Sealed equipment (BioBeam)

30.17 y

Label cells, mice

BioBeam equipment

F - 18

Gamma

Radiotracer (PET machine)

1.83 h

Nuclear medicine

Tc - 99m

Gamma

Radiotracer (PET machine)

6 h

Nuclear medicine

Ra - 224

Alpha

Liquid Sealed needle

3.6 d

Cell research

S - 35

Beta

Liquid

87.9 d

Protein labeling

P - 32

Beta

Liquid

14.3 d

Nucleic acid labeling

H - 3

Beta

Liquid

12.3 y

Label organic molecules; drug discovery

Ca - 45

Beta

Liquid

162.6 y

Calcium metabolism

C - 14

Beta

Liquid

5730 y

Radiocarbon dating

Th - 228

Alpha

Solid

1.91 y

Cell research

Am - 241

Alpha

Solid

432.7 y

Cell research

 

 

  • Isotope Half-life is the time required for one-half of the radioactive atoms in a sample to decay or desintegrate, how fast radioactive material decays

 

  • Appropriate decay waste is 10 half-lives (0.1%)

 

 

 

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