Scientific Program
Four Sessions. One Shared Focus.
Advancing BRCA-Related Malignancies Research Through Multidisciplinary Collaboration
Innovation • Translation • Clinical Impact
| 08:00 - 08:45 | Registration & Coffee |
| 08:45 - 09:00 | Welcome & Greetings Ronit Satchi-Fainaro - Director, CBRC, TAU |
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09:00-10:45 |
Session 1 - Cancer Initiation and Interception in BRCA-Associated Malignancies | Chairs: Adit Ben-Baruch, Rinat Molcho-Bernstein |
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Keynote: Joan Brugge (Harvard): Searching for the Earliest Precursors of Breast Cancer |
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Dana Ishay-Ronen (Sheba): Enhanced Plasticity in Heterozygous BRCA1 Normal Mammary Epithelium Drives Tumorigenic Trajectories |
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Merav Cohen (Medical Sciences, TAU): Immune-controlled signaling niche predisposes breast cancer onset |
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Rinat Yerushalmi (RMC): The Evolving Impact of BRCA Mutations on Therapeutic Strategies |
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Asaf Madi (Medical Sciences, TAU): Spatial Inference of Pathway Activation from Breast Cancer H&E Images |
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Adit Ben-Baruch (Life Sciences, TAU): BRCA1 insufficiency impairs inflammation-induced pro-metastatic effects in TNBC |
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| 10:45 - 11:05 | Coffee Break |
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11:05-12:35 |
Session 2 - Translating BRCA Biology into Clinical Practice | |
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Keynote: Roger Greenberg (UPenn): Targeting Homologous Recombination Deficiency in BRCA Mutant Cancers |
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Keren Levanon (RMC): The Challenge of Early Detection of Ovarian Cancer |
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Yael Raz (TASMC): Counseling in the Gray: Navigating the BRCA Journey When Evidence Is Still Evolving |
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Ilan Tsarfaty (Medical Sciences, TAU): Rethinking BRCA1-Induced Metastasis: Invasive Cell Motility and the Role of Novel Modifier Genes - Multi-omics analysis |
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Talia Golan (Sheba): BRCA-Associated Pancreatic Cancer: Translating Genomic Insights into Clinical Practice |
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| 12:35 - 13:35 | Lunch & Networking |
| 13:35-15:25 |
Session 3 - CBRC-Gray-BRCA Grant Awardees Session | |
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Yael Bar (TASMC): Biomarkers for Neoadjuvant Treatment De-Escalation in BRCA-Related TNBC |
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Shamgar Ben-Eliyahu (Social Sciences, TAU): Molecular Characterization of BRCA-Mutated Ovarian Cancer in the Perioperative Context |
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Yasmin Leshem (TASMC): BRCA-Dependent Responses to TOP1-Based ADC and Immune Sensitization in Breast Cancer |
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Ran Elkon (Medical Sciences, TAU): Discovery of Novel Genetic Modifiers of Breast Cancer Risk in BRCA1 Carriers |
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Gili Bisker (Biomedical Engineering, TAU): Optical Nanosensors for Real-Time Detection of Enzyme Biomarkers |
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Uri Ben-David (Medical Sciences, TAU): BRCA-Driven PDAC: Innovative Models to Study Resistance Mechanisms and Novel Treatment Combinations |
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| Ephrat Levy-Lahad (SZMC): Recipient of the 2026 Basser Global Prize - TBD | |
| 15:25 - 15:45 | Coffee Break |
| 15:45-16:45 |
Session 4 - The Future of BRCA-Related Cancer Research | |
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Keynote: Ronny Drapkin (UPenn): BRCA-Associated Ovarian Cancer: From the Fallopian Tube to Cancer Interception |
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Panel Discussion: What Will Define the Next Decade of BRCA-Related Cancer Research? Moderator: Einav Gal-Yam |
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Closing Remarks: Ronit Satchi-Fainaro |
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| Inquiries: Yehudit Cohen yehuditc@tauex.tau.ac.il | |
Join the Kick-Off Meeting |
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| REGISTER NOW! COLLABORATE | |




