Cancer Biology and Immunology

The Cancer Biology and Immunology department at Tel Aviv University brings together researchers working across basic immunology, cancer biology, and cancer immunology, with the shared goal of understanding how immune and non-immune cells function, interact, and adapt in health and disease. The department’s research addresses fundamental questions in immune regulation, including how immune cells are activated, how tolerance is maintained, and how dysregulation contributes to chronic inflammation, autoimmunity, and immune-mediated pathology. By studying immune responses across diverse physiological contexts, the department advances core immunological knowledge with broad relevance beyond oncology.

In parallel, the department has a strong focus on tumor biology and immuno-oncology, investigating how cancer cells evolve, communicate with their microenvironment, and evade immune control. Research efforts explore the reciprocal interactions between tumors and immune cells, mechanisms of immune suppression and resistance, and the factors that determine disease progression and therapeutic response.

By integrating insights from basic immunology with cancer-focused research, the department fosters a cohesive scientific framework that supports both discovery-driven and translational studies. This combined perspective positions the department as a hub for advancing understanding of immune function and dysfunction while contributing to the development of more effective strategies for cancer treatment and immune-related diseases.

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