Meet Anand Subramaniam
2025 Sieratzki Scholarship Awardee
Anand Subramaniam is a PhD candidate conducting his research under the supervision of Prof. Eran Perlson.
His work focuses on Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative disease characterized by disruption of the neuromuscular junction (NMJ) and progressive motor neuron loss.
Using an induced pluripotent stem cell (iPSC)-based approach, he models a functional humanized NMJ on a microfluidic chip platform to study NMJ-related signaling pathways involved in neurodegeneration.
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This model enables drug testing in patient-specific systems and holds potential to accelerate the discovery of novel therapeutic targets that could preserve NMJ integrity and improve neuronal function. |