Research
Nano-medicine research at Tel Aviv University focuses on:
- Pharmaceutical nano-technologies
- Medical micro systems technologies
- Nano-structures of pathogens
- Self-assembly of nano-structures in living organisms
- Integrated bio-systems on a chip
Research highlights:
- Nanomedicines, the guided missiles for biological enemies within (Haaretz)
- Broken hearts mend with 'patch' (BBC News)
- Killing Cancer Like a Vampire Slayer (American Medical Network)
Research and publications supported by the center:
2024 | |
Nature-inspired peptide of MtDef4 C-terminus tail enables protein delivery in mammalian cells Lucia Adriana Lifshits, Yoav Breuer, Marina Sova, Sumit Gupta, Dar Kadosh, Evgeny Weinberg, Zvi Hayouka, Daniel Z. Bar, and Maayan Gal Scientific Reports 14, 4604 (2024) |
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Kian Kadan-Jamal, Aakash Jog, Marios Sophocleous, Tali Dotan, Polina Frumin, Tamar Kuperberg Goshen, Silvia Schuster, Adi Avni, Yosi Shacham-Diamand Biosensors and Bioelectronics 252, 15 (2024): 116041 |
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2023 |
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Adi Hendler-Neumark, Verena Wulf, and Gili Bisker ACS sensors 8.10 (2023): 3713-3722 |
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Architecture-Based Programming of Polymeric Micelles to Undergo Sequential Mesophase Transitions Parul Rathee, Nicole Edelstein-Pardo, Francesca Netti, Lihi Adler-Abramovich, Amit Sitt, and Roey J. Amir ACS Macro Letters 12 (2023): 814-820 |
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2022 | |
Barak Kagan, Adi Hendler-Neumark, Verena Wulf, Dotan Kamber, Roni Ehrlich, and Gili Bisker Advanced Photonics Research 3.11 (2022): 2200244. |
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Super-Resolution Radial Fluctuations (SRRF) nanoscopy in the near infrared Roni Ehrlich, Verena Wulf, Adi Hendler-Neumark, Barak Kagan, and Gili Bisker Optics Express 30, no. 2 (2022): 1130-1142. |
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Gadi Slor, Shahar Tevet, and Roey J. Amir ACS Polymers Au 2.5 (2022): 380-386. |
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In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice Alessio D. Nahmad, Cicera R. Lazzarotto, Natalie Zelikson, Talia Kustin, Mary Tenuta, Deli Huang, Inbal Reuveni, Daniel Nataf, Yuval Raviv, Miriam Horovitz-Fried, Iris Dotan, Yaron Carmi, Rina Rosin-Arbesfeld, David Nemazee, James E. Voss, Adi Stern, Shengdar Q. Tsai, and Adi Barzel Nature Biotechnology 40, no. 8 (2022): 1241-1249. |
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Frequent aneuploidy in primary human T cells after CRISPR–Cas9 cleavage Alessio David Nahmad, Eli Reuveni, Ella Goldschmidt, Tamar Tenne, Meytal Liberman, Miriam Horovitz-Fried, Rami Khosravi, Hila Kobo, Eyal Reinstein, Asaf Madi, Uri Ben-David, and Adi Barzel Nature Biotechnology 40.12 (2022): 1807-1813. |
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Adaptive sequencing using nanopores and deep learning of mitochondrial DNA Danilevsky, Artem, Avital Luba Polsky, and Noam Shomron. Briefings in Bioinformatics 23.4 (2022): bbac251. |
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Engineered Riboswitch Nanocarriers as a Possible Disease-Modifying Treatment for Metabolic Disorders Shai Zilberzwige-Tal, Danielle Gazit, Hanaa Adsi, Myra Gartner, Rahat Behl, Dana Bar-Yosef Laor, and Ehud Gazit. ACS nano 16, no. 8 (2022): 11733-11741. |
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Spatiotemporal Control of Melanin Synthesis in Liquid Droplets Massarano, Tlalit, Avigail Baruch Leshem, Michal Weitman, and Ayala Lampel. ACS Applied Materials & interfaces 14, no. 18 (2022): 20520-20527. |
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2021 | |
Dendron–Polymer Hybrids as Tailorable Responsive Coronae of Single-Walled Carbon Nanotubes Verena Wulf, Gadi Slor, Parul Rathee, Roey J. Amir, and Gili Bisker. ACS nano 15, no. 12 (2021): 20539-20549. |
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Optical Nanosensors for Real-time Feedback on Insulin Secretion by β-Cells Roni Ehrlich, Adi Hendler-Neumark, Verena Wulf, Dean Amir, and Gili Bisker Small 17.30 (2021): 2101660. |
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Oncometabolite Fingerprinting Using Fluorescent Single-Walled Carbon Nanotubes Dean Amir, Adi Hendler‐Neumark, Verena Wulf, Roni Ehrlich, and Gili Bisker. Advanced Materials Interfaces 9, no. 4 (2022): 2101591. |
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Nicolas Dray, Laure Mancini, Udi Binshtok, Felix Cheysson, Willy Supatto, Pierre Mahou, Sébastien Bedu, Sara Ortica, Emmanuel Than-Trong, Monika Krecsmarik, Sébastien Herber, Jean-Baptiste Masson, Jean-Yves Tinevez, Gabriel Lang, Emmanuel Beaurepaire, David Sprinzak, Laure Bally-Cuif Cell Stem Cell 28.8 (2021): 1457-1472. |
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Shahar Tevet, Shreyas S. Wagle, Gadi Slor, and Roey J. Amir. Macromolecules 54, no. 24 (2021): 11419-11426. |
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Gadi Slor, and Roey J. Amir. Macromolecules 54, no. 4 (2021): 1577-1588. |
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Gadi Slor, Alis R. Olea, Sílvia Pujals, Ali Tigrine, Victor R. De La Rosa, Richard Hoogenboom, Lorenzo Albertazzi, and Roey J. Amir. Biomacromolecules 22, no. 3 (2021): 1197-1210. |
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Aviv, Moran, Dana Cohen-Gerassi, Asuka A. Orr, Rajkumar Misra, Zohar A. Arnon, Linda JW Shimon, Yosi Shacham-Diamand, Phanourios Tamamis, and Lihi Adler-Abramovich. International Journal of Molecular Sciences 22, no. 17 (2021): 9634. |
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Krivitsky, Adva, Sabina Pozzi, Eilam Yeini, Sahar Israeli Dangoor, Tal Zur, Sapir Golan, Vadim Krivitsky, Nitzan Albeck, Evgeny Pisarevsky, Paula Ofek, Asaf Madi, and Ronit Satchi-Fainaro Pharmaceutics 13, no. 12 (2021): 2199. |
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2020 | |
Progress and challenges towards CRISPR/Cas clinical translation Daniel Rosenblum, Anna Gutkin, Niels Dammes, and Dan Peer. Advanced Drug Delivery Reviews 154 (2020): 176-186. |
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Targeted lipid nanoparticles for RNA therapeutics and immunomodulation in leukocytes Veiga, Nuphar, Yael Diesendruck, and Dan Peer. Advanced Drug Delivery Reviews 159 (2020): 364-376. |
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CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy Rosenblum, Daniel, Anna Gutkin, Ranit Kedmi, Srinivas Ramishetti, Nuphar Veiga, Ashley M. Jacobi, Mollie S. Schubert, Dinorah Friedmann-Morvinski, Zvi R. Cohen, Mark A. Behlke, Judy Lieberman, and Dan Peer Science Advances 6, no. 47 (2020): eabc9450. |
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Metasurface-based contact lenses for color vision deficiency Karepov, Sharon, and Tal Ellenbogen Optics Letters 45, no. 6 (2020): 1379-1382. |
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Ultrashort Cell-Penetrating Peptides for Enhanced Sonophoresis-Mediated Transdermal Transport Schnaider, Lee, Leah Shimonov, Topaz Kreiser, Dor Zaguri, Darya Bychenko, Itzchak Brickner, Sofiya Kolusheva, Alexandra Lichtenstein, Joseph Kost, and Ehud Gazit. ACS Applied Bio Materials 3, no. 12 (2020): 8395-8401. |
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2019 | |
Leukocyte-specific siRNA delivery revealing IRF8 as a potential antiinflammatory target Nuphar Veiga, Meir Goldsmith, Yael Diesendruck, Srinivas Ramishetti, Daniel Rosenblum, Eran Elinav, Mark A. Behlke, Itai Benhar, and Dan Peer. Journal of Controlled Release 313 (2019): 33-41. |
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Peles-Strahl, Leigh, Revital Sasson, Gadi Slor, Nicole Edelstein-Pardo, Adi Dahan, and Roey J. Amir Macromolecules 52, no. 9 (2019): 3268-3277. |
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Feiner, Ron, Lior Wertheim, Danielle Gazit, Or Kalish, Gal Mishal, Assaf Shapira, and Tal Dvir. Small 15, no. 14 (2019): 1805526. |
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Basha, Adham, Huarui Fu, George Levi, Gregory Leitus, Andras Kovács, Caiyin You, and Amit Kohn. Journal of Magnetism and Magnetic Materials 489 (2019): 165367. |
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Fs Detuning-modulated composite pulses for high-fidelity robust quantum control Elica Kyoseva, Hadar Greener, and Haim Suchowski. Physical Review A 100, no. 3 (2019): 032333. |
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2018 | |
Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes Veiga, Nuphar, Meir Goldsmith, Yasmin Granot, Daniel Rosenblum, Niels Dammes, Ranit Kedmi, Srinivas Ramishetti, and Dan Peer. Nature Communications 9, no. 1 (2018): 4493. |
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Epigenetic Optical Mapping of 5-Hydroxymethylcytosine in Nanochannel Arrays Gabrieli, Tslil, Hila Sharim, Gil Nifker, Jonathan Jeffet, Tamar Shahal, Rani Arielly, Michal Levi-Sakin, Lily Hoch, Nissim Arbib, Yael Michaeli, and Yuval Ebenstein ACS Nano 12, no. 7 (2018): 7148-7158. |
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Multifunctional degradable electronic scaffolds for cardiac tissue engineering Ron Feiner, Sharon Fleischer, Assaf Shapira, Or Kalish, and Tal Dvir. Journal of Controlled Release 281 (2018): 189-195. |
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Rachel Blau, Yana Epshtein, Evgeni Pisarevsky, Galia Tiram, Sahar Israeli Dangoor, Eilam Yeini, Adva Krivitsky, Anat Eldar-Boock, Dikla Ben-Shushan, Hadas Gibori, Anna Scomparin, Ori Green, Yael Ben-Nun, Emmanuelle Merquiol, Hila Doron, Galia Blum, Neta Erez, Rachel Grossman, Zvi Ram, Doron Shabat, and Ronit Satchi-Fainaro Theranostics 8, no. 13 (2018): 3437. |
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Gibori, Hadas, Shay Eliyahu, Adva Krivitsky, Dikla Ben-Shushan, Yana Epshtein, Galia Tiram, Rachel Blau, Paula Ofek, Joo Sang Lee, Eytan Ruppin, Limor Landsman, Iris Barshack, Talia Golan, Emmanuelle Merquiol, Galia Blum, and Ronit Satchi-Fainaro Nature Communications 9, no. 1 (2018): 16. |
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2017 | |
Cutting-edge platforms in cardiac tissue engineering Fleischer, Sharon, Ron Feiner, and Tal Dvir. Current opinion in biotechnology 47 (2017): 23-29. |
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Tissue–electronics interfaces: from implantable devices to engineered tissues Feiner, Ron, and Tal Dvir. Nature Reviews Materials 3, no. 1 (2017): 1-16 |
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2016 | |
Design of Controllable Bio-Inspired Chiroptic Self-Assemblies Tao, Kai, Guy Jacoby, Luba Burlaka, Roy Beck, and Ehud Gazit Biomacromolecules 17, no. 9 (2016): 2937-2945. |
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Feiner, Ron, Leeya Engel, Sharon Fleischer, Maayan Malki, Idan Gal, Assaf Shapira, Yosi Shacham-Diamand, and Tal Dvir. Nature Materials 15, no. 6 (2016): 679-685. |
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Tao, Kai, Aviad Levin, Lihi Adler-Abramovich, and Ehud Gazit. Chemical Society Reviews 45, no. 14 (2016): 3935-3953. |
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Spontaneous structural transition and crystal formation in minimal supramolecular polymer model Fichman, Galit, Tom Guterman, Joshua Damron, Lihi Adler-Abramovich, Judith Schmidt, Ellina Kesselman, Linda JW Shimon, Ayyalusamy Ramamoorthy, Yeshayahu Talmon, and Ehud Gazit. Science Advances 2, no. 2 (2016): e1500827. |
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2015 | |
Synergetic functional properties of two-component single amino acid-based hydrogels Fichman, Galit, Tom Guterman, Lihi Adler-Abramovich, and Ehud Gazit. CrystEngComm 17, no. 42 (2015): 8105-8112. |
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2014 | |
Fabrication of omentum-based matrix for engineering vascularized cardiac tissues Shevach, Michal, Neta Soffer-Tsur, Sharon Fleischer, Assaf Shapira, and Tal Dvir. Biofabrication 6, no. 2 (2014): 024101. |
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Adler-Abramovich, Lihi, and Ehud Gazit. Chemical Society Reviews 43, no. 20 (2014): 6881-6893. |
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2006 | |
Lihi Adler-Abramovich, Meital Reches, Victoria L. Sedman, Stephanie Allen, Saul JB Tendler, and Ehud Gazit. Langmuir 22, no. 3 (2006): 1313-1320. |
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2005 | |
Self-Assembled Peptide Nanotubes Are Uniquely Rigid Bioinspired Supramolecular Structures Kol, Nitzan, Lihi Adler-Abramovich, David Barlam, Roni Z. Shneck, Ehud Gazit, and Itay Rousso. Nano Letters 5, no. 7 (2005): 1343-1346. |