Prof. Yankel Gabet

I study bone biology and interactions between bone cells and other systems, including osteoimmunology, osteohematology, the gut-bone axis (skeletal roles of the microbiome), sepsis and cancer. 

My research focuses on genetic (human and mouse GWAS, transgenic models), endocrine (sex hormones, erythropoietin, endocannabinoids…), and immunological regulation of bone health. Osteogenic growth peptide, which we demonstrated is an endogenous selective CB2 agonist with important bone anabolic and immunomodulatory functions, is a central theme in my lab. 

We routinely use microcomputed tomography, histomorphometry, biomechanics, and in vitro assays with bone cells (human and murine).  

Being a clinician (oral surgery), former department head and proficient lecturer at the School of Medicine, my research is always bench-to-bedside oriented. We address medical conditions such as osteoporosis, bone fractures, inflammation-induced osteolysis, fibrosis, cancer and cardiovascular diseases. 

I also have broad experience with the industry, as a consultant and inventor, including a patented formula already commercialized for post-infection recovery (https://nviromune.com).