Seminar: Dr. Noam Stern-Ginossar from the Weizmann Institute of Science

Research:  Viruses are completely reliant on the host cell machinery and have evolved many mechanisms to hijack it for their propagation. At the same time our cells have developed defense mechanisms to cope with infections. Dr. Noam Stern-Ginossar's research aims to elucidate the complex cellular changes that occur during these virus-cell encounters. To this end, her lab employs a deep-sequencing technique termed ribosome profiling that allows a comprehensive view of translation events. The robustness, scale, and accuracy of this method dramatically increase our ability to monitor the synthesis of new proteins and provide a unique opportunity to follow the molecular events underlying infection with unprecedented depth. Her lab aims to use this novel resolution to unfold the processes that occur during viral infection and to reveal fundamental cellular principles.